AFM (Active Fuel Management) or DOD (Displacement on Demand) These systems are a real problem for GM. So much so that they are dropping the use on the 5.3 and 6.2 in 2022 and beyond until they can get something to last longer than the first oil change interval. (slight exaggeration)Don't quote me on this, but I think that the GM engines were having issues on the Silverados, Sierras and even the Escalades.
There are a bunch of videos on Youtube about this. Make sure you check that out before buying.
There are ways to work around this, such as installing conventional hyd roller lifters and different pushrods, or the easier solution is to install a Disabler Device in the Data Link connector such as those made by Range Technologies. I have used that on the wife's Suburban with the 5.3. It will drop your average mpg by about 1 mpg but it is worth it to prevent a really costly repair when it goes bad.