In an attempt to not insult anyone, I will just say this...
I would never tune a 5.0 with that setup under any circumstances. In fact, I don't like remote mount systems PERIOD. There are countless reasons and you really don't need me to list them all.
I can see the lure of the cost and ease of install. But we are talking about modifying your $30k, baddest 5.0 Mustang ever built. I don't think it's a good time to pick a modification based on cost or ease install. Not with this car. I could see if it was a low cost car that you just wanted to add some 'zing' to for cheap. But I still wouldn't tune it. lol
ken dont you think you have a rather biased opinion due to the fact you are selling $10,000 turbo kits???